| Supplier | Country | Supplier | Country |
| Alko | Finland | Grindsted Products | Denmark |
| Amano Int. (Europe) | Japan (UK) | Kyowa Hakko Europe | Germany |
| Biocatalysts Ltd. | UK | Larbus S.A. | Spain |
| Biopole | France | Meito Sangyo | Japan |
| Biocon Chemicals Ltd. | Ireland | Miles Laboratories | USA |
| Biozyme | UK | Novo Nordisk | Denmark |
| Boehringer | Germany | Oriental Yeast | Japan |
| Boll | France | Recordati | Italy |
| Calbiochem | USA | Röhm & Haas | Germany |
| Cultor | Finland | Rhone-Poulenc-ABM Brewing | France |
| Dafa S.A. | France | SAF-ISIS | France |
| E. Merk | Germany | Sigma Chemicals | USA |
| Fluka | Switezerland | Solvay Enzymes GmbH | Germany |
| Genencor International | Finland | Stern Enzym GmbH | Germany |
| Genzyme | UK | Toyo Yozo | Japan |
| Girona S.A. | Spain | Viobin Corporation | USA |
| Gist Brocades | The Netherlands | Worthington | USA |
* Despite the several companies producing enzymes, the market as a whole is dominated by the three majorsuppliers: Novo Nordisk holds 50% of the world enzyme sales and Gist Brocades and Rhöm & Haas are the other two major suppliers ( Tucker, G.A., 1996 9).