develop and validate mathematical models and computational tools for the analysis and simulation of the dynamical behavior of complex metabolic networks.
create control and optimization strategies to alter the fluxes and concentrations of metabolites, both transiently and at steady-state, by proposing the manipulation of enzymes gene expression
creation of an integrative bioinformatics infrastructure to store the experimental data and to implement and deploy the algorithms developed
acquisition of experimental in vivo metabolite concentration time series data, the creation of mutant bacterial strains with desired metabolic behavior and the experimental validation of the models previously proposed.

More information at FCT site