cqe
 
 

 

Publications


Latest articles in international journals with refereeing


2014

24) Leonardo Toso, Guido Crisponi, Valeria M. Nurchi, Miriam Crespo-Alonso, Joanna I. Lachowicz, Delara Mansoori, Massimiliano Arca, M. Amélia Santos, Sérgio M. Marques, Lurdes Gano, Juan Niclós-Gutíerrez, Josefa M. González-Pérez, Alicia Domínguez-Martín, Duane Choquesillo-Lazarte, Zbigniew Szewczuk, "Searching for new aluminium chelating agents: A family of hydroxypyrone ligands", J. Inorg. Biochem. 2014, 130, 112-121.
DOI: 10.1016/j.jinorgbio.2013.09.022
[full text here]


2013

23) Leonardo Toso, Guido Crisponi, Valeria M. Nurchi, Miriam Crespo-Alonso, Joanna I. Lachowicz, M. Amelia Santos, Sergio M. Marques, Juan Niclos-Gutierrez, Josefa M. Gonzalez-Perez, Alicia Dominguez-Martin, Duane Choquesillo-Lazarte, Zbigniew Szewczuk, "A family of hydroxypyrone ligands designed and synthesized as iron chelators", J. Inorg. Biochem. 2013, 127, 220-231.
DOI: 10.1016/j.jinorgbio.2013.06.009
[full text here]

22) Sérgio M. Marques, Claudia Abate, Sílvia Chaves, Fernanda Marques, Isabel Santos, Elisa Nuti, Armando Rossello, M. Amélia Santos, "New bifunctional metalloproteinase inhibitors: an integrated approach towards biological improvements and cancer therapy", J. Inorg. Biochem. 2013, 127, 188–202.
DOI: 10.1016/j.jinorgbio.2013.03.003
[full text here]

21) Rangappa S. Keri, Catarina Quintanova, Sérgio M. Marques, A. Raquel Esteves, Sandra M. Cardoso, M. Amélia Santos, "Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease", Bioorg. Med. Chem. 2013, 21, 4559-4569.
DOI: 10.1016/j.bmc.2013.05.028
[full text here]

20) Andreia Nunes, Sérgio M. Marques, Catarina Quintanova, Diana F. Silva, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos, "Multifunctional iron-chelators with protective roles against neurodegenerative diseases", Dalton Trans. 2013, 42, 6058–6073.
DOI: 10.1039/c3dt50406a
[full text here]

19) Ana C. Mendonça, André F. Martins, Andrea Melchior, Sérgio M. Marques, Sílvia Chaves, Sandrine Villette, Stéphane Petoud, Pier Luigi Zanonato, Marilena Tolazzi, Célia S. Bonnet, Éva Tóth, Plinio Di Bernardo, Carlos F.G.C. Geraldes, M. Amélia Santos, "New tris-3,4-HOPO lanthanide complexes as potential imaging probes: complex stability and magnetic properties", Dalton Trans. 2013, 42, 6046-6057.
DOI: 10.1039/C2DT32237D
[full text here]

18) Sílvia Chaves, Anabela Capelo, Laurinda Areias,Sérgio M. Marques, Lurdes Gano, M. Alexandra Esteves, M. Amélia Santos, "A novel tripodal tris-hydroxypyrimidinone sequestering agent for trivalent hard metal ions: synthesis, complexation and in vivo studies", Dalton Trans. 2013, 42, 6033-6045.
DOI: 10.1039/C2DT32361C
[full text here]


2012

17) M. Amélia Santos, Sérgio M. Marques, Sílvia Chaves, “Hydroxypyridinones as “privileged” chelating structures for the design of medicinal drugs”, Coord. Chem. Rev. 2012, 256, 240-259.
DOI: 10.1016/j.ccr.2011.08.008
[full text here]


2011

16) Sérgio M. Marques, Tiziano Tuccinardi, Elisa Nuti, Salvatore Santamaria, Vânia André, Armando Rossello, Adriano Martinelli, and M. Amélia Santos, "1-hydroxypiperazine-2,6-diones as new leads in the inhibition of metalloproteinases”, J. Med. Chem. 2011, 54, 8289-8298.
DOI: 10.1021/jm200593b
[full text here]

15) Jaroslav Šebestík, Sérgio M. Marques, Pedro L. Falé, Susana Santos, Daniela M. Arduíno, Sandra M. Cardoso, Catarina R. Oliveira, M. Luísa M. Serralheiro, M. Amélia Santos, “Bifunctional phenolic-choline conjugates as anti-oxidant and acetylcholinesterase inhibitors”, J. Enzym. Inhib. Med. Ch. 2011, 26, 485-497.
DOI: 10.3109/14756366.2010.529806

[full text here]

14) Sílvia Chaves, Ana C. Mendonça, Sérgio M. Marques, M. Isabel Prata, Ana C. Santos, André F. Martins, Carlos F.G.C. Geraldes, M. Amélia Santos, “A gallium complex with a new tripodal tris-hydroxypyridinone for potential nuclear diagnostic imaging: solution and in vivo studies of 67Ga-labeled species”, J. Inorg. Biochem. 2011, 105, 31-38.
DOI: 10.1016/j.jinorgbio.2010.09.012
[full text here]


2010 and earlier

13) Sílvia Chaves, Sérgio M. Marques, André M.F. Matos, Andreia Nunes, Lurdes Gano, Tiziano Tuccinardi, Adriano Martinelli, M. Amélia Santos, "New tris-hydroxypyridinones as iron and aluminum sequestering agents. Synthesis, complexation and in vivo studies”, Chem.-Eur. J. 2010, 16, 10535-10545.
DOI: 10.1002/chem.201001335
[full text here]

12) Sérgio M. Marques, Éva A. Enyedy, Claudiu T. Supuran, Natalia I. Krupenko, Sergey A. Krupenko and M. Amélia Santos, “Pteridine–sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity”, Bioorg. Med. Chem. 2010, 18, 5081-5089.
DOI: 10.1016/j.bmc.2010.05.072
[full text here]

11) M. Alexandra Esteves, Osvaldo Ortet, Anabela Capelo, Claudiu T. Supuran, Sérgio M. Marques and M. Amélia Santos, “New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors”, Bioorg Med. Chem. Lett. 2010, 20, 3623-3627.
DOI: 10.1016/j.bmcl.2010.04.109
[full text here]

10) Tiziano Tuccinardi, Gabriella Ortore, M. Amélia Santos, Sérgio M. Marques, Elisa Nuti, Armando Rossello and Adriano Martinelli, “Multitemplate alignment method for the development of a reliable 3D-QSAR model for the analysis of MMP3 inhibitors”, J. Chem. Inf. Model. 2009, 49, 1715-1724.
DOI: 10.1021/ci900118v
[full text here]

9) Sérgio M. Marques, Elisa Nuti, Armando Rossello, Claudiu T. Supuran, Tiziano Tuccinardi, Adriano Martinelli and M. Amélia Santos, “Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl based hydroxamate-benzenesulfonamide conjugates”, J. Med. Chem. 2008, 51, 7968-7979.
DOI: 10.1021/jm800964f
[full text here]

 

Patents

2) Sérgio M. Marques, Armando Rossello, M. Amélia Santos, “New inhibitors of metalo-enzymes with potential clinical application: 1-hydroxy-piperazino-2,6-dione derivatives as a new zinc-binding group”, PT 103897, 2008.
[full text here]

1) M. Amélia Santos, Sérgio M. Marques, Marco Gil, Matteo Tegoni, Sílvia Chaves, “Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacity”, PT 103003, 2005.

 

Conference proceedings with scientific refereeing

2) Sérgio M. Marques, Sílvia Chaves, Armando Rossello, Tiziano Tuccinardi and M. Amélia Santos, “Iminodiacetyl-monohydroxamate derivatives as potent and selective MMP inhibitors”, Metal Ions in Biology and Medicine, John Libbey Eurotext: Paris, 2006, Vol. 9, p. 117-121.
[full text here]

1) M. Amélia Santos, Marco Gil, Sérgio Marques, M. Lurdes Gano, Sílvia Chaves, “Complexation of three N-carboxyalkyl derivatives of 3-hydroxy-4-pyridinones with Fe(III), Al(III), Ga(III) and In(III). Studies in vitro and in vivo”, Metal Ions in Biology and Medicine, John Libbey Eurottext: Paris, 2002, Vol. 7, pp 655-658.

 

Copyright © 2012 by Sérgio M. Marques