Carlos Baleizão

 
 
Principal Researcher

Centro de Química-Física Molecular
Instituto Superior Técnico
University of Lisbon
Av. Rovisco Pais
1049-001 Lisboa
Portugal
 
office: 518 (Complexo Interdisciplinar)
phone: (+351) 218 419 206
email: carlos.baleizao[@]tecnico.ulisboa.pt
 

  Education
Professional Appointments
Prizes and Awards
Research Interests
Projects
Team       
Teaching
Other Activities
Publications

Lectures

 

 

 

 

 


Education top  
2004 Ph.D. in Chemistry (Technical University of Lisbon).
The experimental part was developed at Instituto Nacional de Engenharia, Tecnologia e Inovação (Portugal) under the guidance of Dra. Bárbara Gigante and Instituto de Tecnologia Quimica/Universidade Politecnica de Valencia (Spain) under the supervision of Prof. Hermenegildo Garcia and Prof. Avelino Corma, working on nanostructured hybrid materials for asymmetric catalysis
 
 
1999 Graduation in Chemistry - organic chemistry major (Universidade NOVA de Lisboa)  
 

Professional Appointments top  

since 2013

Principal Researcher of IST (University of Lisbon) at Centro de Química-Física Molecular, under the "Investigador FCT" program and integrated member of the Associated Laboratory IN-Institute of Nanoscience and Nanotechnology
 
 
2008-2012 Assistant Researcher of IST at Centro de Química-Física Molecular, under the "Ciência 2007" program
"Ciência 2007" program was an international call for applications for Ph.D. research positions

 
 
2004-2007 Post-doctoral fellow
Otto S. Wolfbeis (Institute of Analytical Chemistry, Chemo- and Biosensors/University of Regensburg/Germany) and Mário Nuno Berberan-Santos (Centro de Química-Física Molecular, IST), working on optical sensors based on polymeric materials and fullerenes
 
 

   
 

Prizes and Awards top  
2012 FCT Investigator - Development grant
("Investigador FCT" 2012 call, Carlos Baleizão was ranked in the first 80 out of 1200 applications from all areas of knowledge)
 
2011 Winner of the “Scientific Prizes UTL/Santander Totta 2011" in the field of "Environment, Chemical Engineering and Chemistry"
(based on scientific productivity, citations and impact factor criteria)
 
2008 Winner of the “Technical University of Lisbon Young Researchers Prize" in the field of "Chemical Engineering, Chemistry, Materials and Nanotechnology"
(based on scientific productivity, citations and impact factor criteria)
 
2005 Portuguese winner of the International FISOCAT award for Young Researchers (Best PhD thesis in Catalysis and Porous Materials)
(Catalysis and Porous Materials Division of the Portuguese Chemical Society)
 
2003 Post-Doctoral Fellowship from Fundação para a Ciência e a Tecnologia (FCT)-Portugal  
2000 Ph.D. Fellowship from Fundação para a Ciência e a Tecnologia (FCT)-Portugal  
 

Research Interests top  
 

Hybrid silica nanoparticles for imaging and theranostics

Development of hybrid silica nanoparticles (diameter between 30 and 300 nm) with fluorescent molecules incorporated in the silica network. Compact nanoparticles are obtained through the Stöber method, using organic fluorescent molecules with alkoxysilane groups as secondary silica source, to obtain hybrid nanostructures. Additionally, the external surface can be easily modified for targeting and increased biocompatibility. Mesoporous silica nanoparticles (MSNs) are obtained using a modified sol-gel process using a template and achieving porous with diameter around 2-3 nm. The MSNs external surface can be selectively functionalized to immobilize polymers or (bio)molecules for possible targeting or sensing, and the pore is available for solvent diffusion, allowing the incorporation of different molecules. MSNs are excellent candidates for stimuli-responsive controlled-release systems carrying different functionalities for theranostics. 

 

 

 

 

 

 

  "High performance NIR fluorescent silica nanoparticles for bioimaging", T. Ribeiro, S. Raja, A. S. Rodrigues, F. Fernandes, J. P. S. Farinha*, C. Baleizão*, RSC Advances, 2013, 3, 9171-9174  

"Intrinsically fluorescent silica nanocontainers: a promising theranostic platform",  A. S. Rodrigues, T. Ribeiro, F. Fernandes, J. P. S. Farinha*, C. Baleizão*, Microscopy and Microanalysis, 2013, 19, 1216-1221

   
 
 

Photoactive MOFs and COFs for energy applications

Development of new photoactive metal organic frameworks (MOFs) incorporating homo- or hetero- fluorescent ligands using different clusters (Zn, Zr, Cu, etc) for application as light harvesting material and semiconductors in solar cells or electroluminescent devices.
Covalent Organic Frameworks (COFs) based in fluorescent ligands for energy applications.

 

 

 

 

   
  Photoactive MOFs   Photoactive COFs    
 
 

Synthesis of perylenediimides (PDIs) 

Our objective is the development of new functionalize perylenediimides (PDIs) for incorporation in nanostructure materials. The introduction of substituent's in the imide region will affect the solubility or allow their immobilization, and substituent's in the bay region (perylene core) will affect the electronic and optical properties. The new functional groups are chosen depending on the selected application.

 

 

 

  

 

 

 
 

Optical Fluorescent Sensors

Development of new optical fluorescent sensors based on inorganic complexes or organic molecules for continuous recording of chemical species or physical parameters. The new sensors are usually immobilized in matrices like polymers or silica materials to increase the range of applicability.

 

 

 

 

 

 

 

"Oxygen-Proof Fluorescence Temperature Sensing with Pristine C70 Encapsulated in Polymer Nanoparticles", V. Augusto, C. Baleizão*, M. N. Berberan-Santos, J. P. S. Farinha*, Journal of Materials Chemistry, 2010, 20, 1192-1197

 

"Sensing and imaging of oxygen with ppb limits of detection and based on the quenching of the delayed fluorescence of 13C70 fullerene in polymer hosts", S. Kochmann, C. Baleizão*, M. N. Berberan-Santos*, O. S. Wolfbeis*, Analytical Chemistry, 2013, 85, 1300-1304

   
 

Research Projects top  
"SolarNHyMat - Nanostructured Hybrid Materials for Solar Cells"
Coordinator: Carlos Baleizão
Partners: CQFM-IST and Instituto de Telecomunicações - Lisboa (Jorge Morgado)
Funding Source: Fundação para a Ciência e a Tecnologia

Total Budget: 180 k€
 
 
"SAFUEL - The SAfer FUEL system"
Contact Point at IST: Carlos Baleizão
Partners: Zodiac Aerospace (Coordinator, France), Airbus (UK), Aston University (UK), Cranfield University (UK), TU Hamburg (Germany), Naples University (Italy), Lille University (France),  IST (Portugal), CNR (Italy), NLR (Netherlands),
ARTTIC (France), Nedaero (Netherlands), Telemaq (France)
Funding Source: EC-FP7 (2012 - 2015)

Total Budget: 7.4 M€
 
 

Team top  
  André Costa, Post-Doc

Ph.D. (2011) in Chemistry, ITQB (Portugal)

Synthesis of new perylenediimides.
Development of photoactive MOFs.

    Raja Sebastian, Post-Doc

Ph.D. (2010) in Synthetic Organic Chemistry, University of Madras (India)

Synthesis of new perylenediimides. Development of photoactive organic frameworks.

 
 

  Ana Sofia Rodrigues, Ph.D. student
(co-supervision with José Paulo Farinha)

M.Sc. (2011) in Chemistry, FC/UL (Portugal)

Nanostructured Stimuli-Responsive Hybrid Materials for Controlled Drug Release.

   

Suzete Almeida, Research Grantee
(co-supervision with José Gaspar Martinho)

M.Sc. (2010) in Chemistry, FC/UP (Portugal)

Controlled polymerizations and synthesis of fluorescent molecules.

 
 

  Gonçalo Adriano, M.Sc. student
(co-supervision with José Paulo Farinha)

B.Sc. (2012) in Bioelectronics Engineering, IPS (Portugal)

Stimuli-Responsive Nanofiber Scaffolds for Stem Cells Production.

 

 

Elizabete Coutinho, M.Sc. student
(co-supervision with José Paulo Farinha)

B.Sc. (2012) in Biomechanical Engineering, IPL (Portugal)

Hybrid Mesoporous Silica Smart Nanocontainers. 

 
 

Teaching top  

2013/2014

-
"Green Technologies and Strategic Management" course (Masters Degree in Chemical Engineering, Biological Engineering, Biotechnology and Bioengineering and Nanosystems), Instituto Superior Técnico (proposed and developed in collaboration with Frederico Ferreira, since 2009).

- Academic Staff of "Nanostructured 0-3D Materials" and "Nanomaterials and Nanotechnologies" courses, FCT PhD Program in Advanced Materials and Processing (AdvaMTech).

- Academic Staff of "Materials for Regenerative Medicine" course, FCT PhD Program in Bioengineering – Cell Therapies and Regenerative Medicine.

 
 

Other Activities top  
- Assistant Editor of QUÍMICA-Portuguese Chemical Society Bulletin (since 2010).

- co-Chair of "ChemULisboa - Novos desafios da Química na nova ULisboa" (April-July 2014).

- co-Chair of "4 Jornadas Ibéricas de Fotoquímica (4'JIF)", Lisboa, Portugal, June 29-July 2 of 2014.

- co-Founder (2008) and co-President (2008-2010) of the Young Chemists Group of the Portuguese Chemical Society.

- Chairman of the 1st Portuguese Young Chemists Meeting (1PYCheM), Lisboa, Portugal, 15 to 17 of October 2008.

 
 

Publications top  

Papers

P42.           G. Periyasami, L. Martelo, C. Baleizão, M. N. Berberan-Santos
Strong Green Chemiluminescence from Naphthalene Analogues of Luminol.
New Journal of Chemistry, 2014, in press.

P41.           S. Martins, J. P. S. Farinha, C. Baleizão, M. N. Berberan-Santos
Controlled release of singlet oxygen using diphenylanthracene functionalized polymer nanoparticles.
Chemical Communications, 2014, 50, 3317-3320.

P40.           T. Ribeiro, S. Raja, A. S. Rodrigues, F. Fernandes, C. Baleizão, J. P. S. Farinha  
NIR and Visible Perylenediimide-Silica Nanoparticles for Laser Scanning Bioimaging.
Dyes and Pigments, 2014, in press.

P39.           A. Agrebi, F. Allouche, F. Chabchoub, S. Alves, C. Baleizão, J. P. S. Farinha, L. El-Kaim
Sc(OTf)3 promoted multicomponent synthesis of fluorescent imidazo[1,2-c]pyrazolo[3,4-d]pyridimidine.
Tetrahedron Letters, 2013, 54, 4781-4784.

P38.           M. A. Esteves, B. Gigante, C. Santos, A. M. Guerreiro, C. Baleizão
New heterogeneous catalysts for the synthesis of chiral amino acids: functionalization of organic resins with chiral salen complexes.
Catalysis Today, 2013, 218-219, 65-69.

P37.           P. Remón, C. P. Carvalho, C. Baleizão, M. N. Berberan-Santos, U. Pischel
Highly Efficient Singlet-Singlet Energy Transfer in Light-Harvesting [60,70]Fullerene- 4-Amino-1,8-naphthalimide Dyads.
ChemPhysChem, 2013, 14, 2717-2724.

P36.           T. Ribeiro, A. Fedorov, C. Baleizão, J. P. S. Farinha
Formation of hybrid films from perylenediimide-labeled core–shell silica–polymer nanoparticles.
Journal of Colloid and Interface Science, 2013, 401, 14-22.

P35.           T. Ribeiro, S. Raja, A. S. Rodrigues, F. Fernandes, J. P. S. Farinha, C. Baleizão
High performance NIR fluorescent silica nanoparticles for bioimaging.
RSC Advances, 2013, 3, 9171-9174.

P34.           A. S. Rodrigues, T. Ribeiro, F. Fernandes, J. P. S. Farinha, C. Baleizão
Intrinsically fluorescent silica nanocontainers: a promising theranostic platform.
Microscopy and Microanalysis, 2013, 19, 1216-1221.

P33.           S. Kochmann, C. Baleizão, M. N. Berberan-Santos, O. S. Wolfbeis
Sensing and imaging of oxygen with ppb limits of detection and based on the quenching of the delayed fluorescence of 13C70 fullerene in polymer hosts.
Analytical Chemistry, 2013, 85, 1300-1304.

P32.           F. Menezes, A. Fedorov, C. Baleizão, B. Valeur, M. N. Berberan-Santos
Methods for the analysis of complex fluorescence decays: Sum of Becquerel functions versus sum of exponentials.
Methods and Applications in Fluorescence, 2013, 1, 015002.

P31.           C. Baleizão, M. N. Berberan-Santos
Enzyme kinetics with a twist.
Journal of Mathematical Chemistry, 2011, 49, 1949-1960.

P30.           C. Baleizão, M. N. Berberan-Santos
The Brightest Fullerene: A New Isotope Effect in Molecular Fluorescence and Phosphorescence.
ChemPhysChem, 2011, 12, 1247-1250.(Cover of ChemPhysChem Issue 7/2011)

P29.           R. Ferreira, C. Baleizão, J. Munoz-Molina, M. N. Berberan-Santos, U. Pischel
Photophysical Study of Bis-naphthalimide - Amine Conjugates: Towards Molecular Design of Excimer Emission Switching.
Journal Physical Chemistry A, 2011, 115, 1092-1099.

P28.           S. Martins, A. Fedorov, C. A. M. Afonso, C. Baleizão, M. N. Berberan-Santos
Fluorescence of Fullerene C70 in Ionic Liquids.
Chemical Physics Letters, 2010, 497, 43-47.

P27.           C. Baleizão, M. N. Berberan-Santos
External heavy-atom effect on the fluorescence of [70]fullerenes.
ChemPhysChem, 2010, 11, 3133-3140.

P26.           V. Augusto, C. Baleizão, M. N. Berberan-Santos, J. P. S. Farinha
Oxygen-Proof Fluorescence Temperature Sensing with Pristine C70 Encapsulated in Polymer Nanoparticles.
Journal of Materials Chemistry, 2010, 20, 1192-1197.

P25.           T. Ribeiro, C. Baleizão, J. P. S. Farinha
Synthesis and Characterization of Perylenediimide Labeled Core-Shell Hybrid Silica-Polymer Nanoparticles.
Journal of Physical Chemistry C, 2009, 113, 18082-18090.

P24.           C. Baleizão, M. N. Berberan-Santos
How Fast is a Fast Equilibrium? A New View of Reversible Reactions.
ChemPhysChem, 2009, 10, 199-205.

P23.           C. Baleizão, S. Nagl, M. Schäferling, M. N. Berberan-Santos, O. S. Wolfbeis
Dual Fluorescence Sensor for Trace Oxygen and Temperature with Unmatched Range and Sensitivity.
Analytical Chemistry, 2008, 80, 6449-6457.

P22.           C. Baleizão, M. N. Berberan-Santos
Thermally Activated Delayed Fluorescence in Fullerenes.
Annals of the New York Academy of Sciences, 2008, 1130, 224-234.

P21.           C. Baleizão, M. N. Berberan-Santos
Thermally activated delayed fluorescence as a fast cycling process between excited singlet and triplet states. Application to the fullerenes.
Journal of Chemical Physics, 2007, 126, 204510.

P20.           C. Baleizão, S. Nagl, S. Borisov, M. Schäferling, O. S. Wolfbeis, M. N. Berberan-Santos
Optical Thermometer Based on the Delayed Fluorescence of C70.
Chemistry: A European Journal, 2007, 13, 3643-3651.

P19.           S. Nagl, C. Baleizão, S. Borisov, M. Schäferling, O. S. Wolfbeis, M. N. Berberan-Santos
Record Response Optical Trace Oxygen Sensing and Imaging.
Angewandte Chemie International Edition, 2007, 46, 2317-2319. (Chosen as a "Hot Paper" by the Editors of Angewandte Chemie)

P18.      C. Baleizão, H. Garcia
Chiral salen complexes: an overview to recoverable and reusable homogeneous and heterogeneous catalysts.
Chemical Reviews, 2006, 106, 3987-4043.

P17.           M. Rae, F. Perez-Balderas, C. Baleizão, A. Fedorov, A. S. Cavaleiro, A. Tomé, M. N. Berberan-Santos
Intra- and Intermolecular Heavy-Atom Effects on the Fluorescence Properties of Brominated C60 Polyads.
Journal of Physical Chemistry B, 2006, 110, 12809-12814.

P16.           C. Baleizão, M. N. Berberan-Santos
A molecular thermometer based on the delayed fluorescence of C70 dispersed in a polymer film.
Journal of Fluorescence, 2006, 16, 215-218.

P15.            I. Oueslati, R. A. S. Ferreira, L. D. Carlos, C. Baleizão, M. N. Berberan-Santos, B. de Castro, J. Vicens, U. Pischel
Calix[4]azacrowns as Novel Molecular Scaffolds for Generation of Visible and Near-Infrared Lanthanide Luminescence.
Inorganic Chemistry, 2006, 45, 2652-2660.

P14.           M. Alvaro, C. Baleizão, E. Carbonell, M. El Ghoul, H. García, B. Gigante
Polymer-bound aluminium salen complex as reusable catalysts for CO2 insertion into epoxides.
Tetrahedron, 2005, 61, 12131-12139.

P13.           M. Alvaro, C. Baleizão, D. Das, E. Carbonell, H. García
CO2 fixation using recoverable chromium salen catalysts. Use of ionic liquids as co-solvent or high-surface area silicates as supports
Journal of Catalysis, 2004, 228, 254-258.

P12.           C. Baleizão, B. Gigante, H. Garcia, A. Corma
Chiral vanadyl salen complex anchored on solid supports as heterogeneous catalysts for the enantioselective cyanosilylation of aldehydes. Comparison between silicas, carbon nanotubes, activated carbons and ionic scaffolds.
Tetrahedron, 2004, 60, 10461-10468.

P11.           C. Baleizão, N. Pires, B. Gigante, M. J. Marcelo Curto
Friedel-Crafts reactions in ionic liquids: the counter-ion effect on the selectivity of dealkylation and acylation of methyl dehydroabietate.
Tetrahedron Letters, 2004, 45, 4375-4377.

P10.           C. Baleizão, B. Gigante, D. Das, M. Alvaro, H. Garcia, A. Corma
Periodic Mesoporous Organosilica: incorporation of a catalytically active vanadyl Schiff base complex in the framework.
Journal of Catalysis, 2004, 223, 106-113.

P9.                C. Baleizão, B. Gigante, H. Garcia, A. Corma
Vanadyl salen complexes covalently anchored to single wall carbon nanotubes as heterogeneous catalyst for the cyanosilylation of aldehydes.
Journal of Catalysis, 2004, 221, 77-84.

P8.                C. Baleizão, A. Corma, H. Garcia, A. Leyva
Oxime carbapalladacycle covalently anchored to high surface area inorganic supports or polymers as heterogeneous green catalysts for the Suzuki reaction in water.
Journal of Organic Chemistry, 2004, 69, 439-446.

P7.               C. Baleizão, B. Gigante, F. Ramoa Ribeiro, B. Ferrer, E. Palomares, H. Garcia
Photochemistry of chiral pentacoordinated Al salen complexes. Chiral recognition in the quenching of photogenerated tetracoordinated Al salen transient by alkenes.
Photochemical & Photobiological Sciences, 2003, 2, 386-392.

P6.               C. Baleizão, A. Corma, H. Garcia, A. Leyva
An oxime-carbapalladacycle complex covalently anchored to silica as active and reusable heterogeneous catalyst for the Suzuki cross coupling in water.
Chemical Communications, 2003, 606-607.

P5.               C. Baleizão, B. Gigante, H. Garcia, A. Corma
Chiral vanadyl Schiff base complex anchored on silicas as solid enantioselective catalysts for formation of cyanohydrins.
Journal of Catalysis, 2003, 215, 199-207.

P4.                C. Baleizão, B. Gigante, D. Das, M. Alvaro, H. Garcia, A. Corma
Synthesis and Catalytic Activity of a Chiral Periodic Mesoporous Organosilica (ChiMO).
Chemical Communications, 2003, 1860-1861.

P3.               C. Baleizão, B. Gigante, H. Garcia, A. Corma
Vanadyl salen complexes covalently anchored to imidazolium ion as catalyst for the cyanosilylation of aldehydes in ionic liquids.
Tetrahedron Letters, 2003, 44, 6813-6816. ("Top-50 most cited articles" as published in Tetrahedron Letters 2003-2006)

P2.               C. Baleizão, B. Gigante, M. J. Sabater, H. Garcia, A. Corma
On the activity of chiral chromium salen complexes covalently bound to solid silicates for the enantioselective epoxide ring opening.
Applied Catalysis A: General, 2002, 228, 279-288.

P1.               C. Baleizão, B. Gigante, H. Garcia, A. Corma
Ionic Liquids as solvents for the asymmetric synthesis of cyanohydrins catalysed by VO(salen) complexes.
Green Chemistry, 2002, 4, 272-274.

Number of citations (ISI WoK, March 2014): >1660

Book Chapters

BC2.      M. N. Berberan-Santos, C. Baleizão
            Fluorescence Sensing of Temperature and Oxygen with Fullerenes, in Molecules at Work: Selfassembly, Nanomaterials, Molecular Machinery
            Wiley-VCH: Berlin, 2012, pp. 285-313.

BC1.     S. Nascimento, C. Baleizão, M. N. Berberan-Santos
            Fluorescence of Fullerenes, in Fluorescence of Supermolecules, Polymers and Nanosystems, Springer: Berlin, 2008.
           
Springer Ser. Fluoresc., 2008, 4, 151-184.

 
 

Lectures in Congresses, Meetings and Universities top  

L24.          1st International Congress on Chromogenic and Emissive Materials (IC3EM 2014)
Caparica (Portugal), September 2014, Invited Oral Communication - UPCOMING

L23.          X National Meeting of the Inorganic Chemistry Division of the Portuguese Chemical Society
Caparica (Portugal), April 2014, Oral Communication

L22.           II National Meeting of Chemistry Students
Covilhã (Portugal), March 2014, Invited Oral Communication

L21.           IX National Meeting of the Catalysis and Porous Materials Division of the Portuguese Chemical Society
Oporto (Portugal), May 2013, Invited Oral Communication

L20.           Applied 4 Chemistry Conferences, Chemistry Department, Universidade Nova de Lisboa
Caparica (Portugal), April 2013, Invited Lecture

L19.           Chemforum Conferences, Centro de Química Estrutural, Instituto Superior Técnico
Lisbon (Portugal), April 2013, Invited Lecture

L18.      Third International Conference on Multifunctional, Hybrid and Nanomaterials (Hybrid Materials 2013)
Sorrento (Italy), March 2013, Oral Communication

L17.           Lisbon School of Health Technology, Polytechnic Institute of Lisbon
Lisbon (Portugal), June 2012, Invited Lecture

L16.           3rd Portuguese Young Chemists Meeting
Oporto (Portugal), May 2012, Invited Oral Communication

L15.           III Iberian Meeting on Photochemistry
Granada (Spain), September 2011, Oral Communication

L14.           X Photochemistry National Meeting of the Portuguese Chemical Society
O
porto (Portugal), December 2010, Invited Oral Communication

L13.           3rd European Chemistry Congress
Nuremberg (Germany), September 2010, Oral Communication

L12.           Chemistry Department, University of Évora
Évora (Portugal), June 2010, Invited Lecture

L11.           Ciência 2009 Meeting, Council of Associated Laboratories
Lisbon (Portugal), July 2009, Invited Oral Communication

L10.           Ciência 2008 Meeting, Council of Associated Laboratories
Lisbon (Portugal), July 2008, Invited Oral Communication

L9.                XXI National Meeting of Portuguese Chemical Society
Oporto (Portugal), June 2008, Invited Oral Communication

L8.                VIII National Meeting of the Catalysis and Porous Materials Division of the Portuguese Chemical Society
Lamego (Portugal), September 2007, Oral Communication

L7.               II Iberian Meeting on Photochemistry
Faro (Portugal), July 2007, Invited Oral Communication

L6.               VI National Meeting of the Analytical Chemistry Division of the Portuguese Chemical Society
Lisbon (Portugal), March 2007, Oral Communication

L5.               Chemistry Department, Universidade Nova de Lisboa
Caparica (Portugal), December 2006, Invited Lecture

L4.               210th Electrochemistry Society Meeting
Cancun (Mexico), November 2006, Oral Communication

L3.               XII International Symposium on Luminescence Spectrometry
Lugo
(Spain), July 2006, Oral Communication

L2.               VIII Photochemistry National Meeting of the Portuguese Chemical Society
Coimbra
(Portugal), December 2005, Oral Communication

L1.               French-Spanish meetings of Organic Chemistry
Peñiscola
(Spain), June 2002, Oral Communication

 
 

Last Update: March 2014